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In vitro fertilization is a procedure that has helped couples around the world get pregnant in a safe manner. In this procedure, sperm from the male partner, or donor sperm, and eggs from the female partner, or donor eggs, are combined in a laboratory to form embryos. Embryos are then transferred to the woman's uterus, where they may implant and develop into a child.

For all of its fame and glory, however, in vitro fertilization is not a sure thing. Most couples know this going in. Certain factors may increase or decrease a couple's chances of success, such as the age of the woman and the overall health of both partners. According to some reports, the success of in vitro fertilization using fresh non-donor eggs is around 39%, although reports vary. Some indicate the overall success rates of in vitro fertilization to be much lower, while others show success rates much higher.

There are certain things that couples may do to increase their chances of success, such as turning to intracytoplasmic sperm injection (ICSI) for men with poor sperm quality. This procedure involves the direct injection of a single sperm into a mature egg to form an embryo. This has helped many men with poor sperm quality achieve success near the same level of success enjoyed by men with a healthy semen analysis during in vitro fertilization.

What worries many couples is the price of in vitro fertilization and other fertility treatments. Success on the first attempt is not guaranteed, and fertility clinics do not offer refunds for failed cycles. That leaves many couples hoping for success on their first attempt. Freezing embryos is an option that some couples take advantage of to save money on subsequent cycles, although using frozen embryos has been reported to decrease the chances of success.

There are, however, plenty of first attempt success stories out there that give hope to many couples. It is important not to expect success with any fertility treatment, but hope cannot hurt one's chances. Internet forums, counseling groups and other resources available through fertility clinics may offer many encouraging stories of women who have had success on their first in vitro fertilization cycle.

Couples exploring in vitro fertilization may also find it helpful to explore alternative treatments designed to reduce stress and improve reproductive health , as stress can have a largely negative impact on a couple's ability to conceive. Many recommend yoga, acupuncture and fertility massage months before undergoing treatment.


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