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THE FACTS
People who suffer from chronic headaches have been known to try all sorts of pills and home remedies. But cayenne peppers?
Behind the folk wisdom is capsaicin, the active ingredient in cayenne. It is said to bring relief by depleting Substance P, a neurotransmitter that helps transmit pain impulses. Sounds unlikely, but a number of studies have tested the claim, and most have found evidence to support it.
One prominent study was published in 1998 in The Clinical Journal of Pain by researchers in the department of anasthesia and critical care at the University of Chicago. In it, the researchers analyzed data from 33 prior studies and found that capsaicin seemed to work better than placebos for headaches occurring in clusters.
But simply eating hot sauce isnt going to help. Most studies suggest that capsaicin works just when applied topically. A study by researchers at Massachusetts General Hospital recruited sufferers of chronic headaches and randomly split them. One group had small amounts of diluted capsaicin applied inside the nose for a week. The other received placebo. The study found a significant decrease in headache severity in the capsaicin group, but not the placebo group. Other studies, including one this year, published similar results.
What it's for: Migraine, cluster and tension headaches or for allergy and sinus relief. Some consumers are also using it for snoring, according to Paul Carpenter, the product's creator.
Capsaicin and cancer
In the journal "Cancer Research," researchers reported that capsaicin led 80 per cent of human prostrate cancer cells growing in mice to destroy themselves in a process of cell suicide. "It also dramatically slowed the development of prostate tumors formed by those human cell lines grown in mouse models," said Dr Soren Lehmann of the Cedars-Sinai Medical Center and the University of California, Los Angeles, who wrote in the journal. Another study, presented at the American Association for Cancer Research, showed that capsaicin could fight pancreatic cancer.
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