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Stem cell treatment is a minefield of false claims and misleading advertising and it takes a strict set of guidelines , which can be followed easily by a lay person, to safely choose what is appropriate. This article was written by the medical director of Regenecell to inform the public how to avoid the pitfalls of an incorrect decision. The information contained in this article comes from years of meticulous research in the field and the experience of consulting stem cell companies in the treatment of over 800 patients. The points listed below arenot negotiablewhen deciding on appropriate stem cell therapy. Relenting on any of these points can lead to a non-response or an adverse reaction, which can have lifelong implications. Please be meticulous when deciding on who treats you. Leave nothing to chance and be careful from where and from whom you take your advice.
1. Stem cell therapy offers no guarantees and is not a cure for any disease.
2. Anecdotal evidence, personal experience or information offered on blogs offer no proof of therapy outcomes and can be dangerously biased. It can give you an idea of what the clinic is like in terms of service and facilities, but should not be relied upon to make a decision for treatment. Accepting a recommendation from a person on a blog is extremely dangerous.
3. Only accept treatment from a company that uses cells from a facility which maintains "Good Manufacturing Practice" or "GMP". Without this assurance, the cells may be impure and lead to tumour formation or Graft vs Host disease.
4. Cortisone (steroid) or non-steroidal anti-inflammatories do not belong anywhere in the treatment process. Their use will inhibit engraftment and mask any adverse events. This will lead to a failed response to the treatment. Stem cells rely on inflammation to guide their homing and this is switched off by any anti-inflammatory - resulting in no treatment response.
5. Multiple invasive procedures confer no extra benefit, and lead to higher risk of contamination, infection and results in greater trauma and therefore less response to therapy. The reason for the lesser response is that trauma is inflammation and attracts stem cells, which are wasted on the damage caused, and not on the disease the patient wanted treatment for in the first place. In addition, repeated lumbar punctures can lead to long-term back pain.
6. Cells should be given separately and the exact numbers should be detailed on the certificate of analysis which must specify each vial. Mixtures should not be used and purity must be listed.
7. Current evidence shows that Mesenchymal cells should always be used to gain an optimal effect.
8. Lengthy treatment times are unnecessary. No benefit over one week has been demonstrated.
9. Intravenous treatment is not enough for neurological conditions in some patients over the age of 12.
10. Umbilical cord cells are the safest and most effective. Your own cells can be as effective in certain circumstances, but provide no additional safety. Embryonic and fetal cells could offer unknown risks.
11. Treatment without growth factors is pointless. This is because stem cells will not remain in the circulation unless forced to, and will immediately migrate into the bone marrow where they remain dormant and do not become active without being stimulated artificially to do so. Stem cells will only work if they are in our blood vessels or central nervous systems, not our bone marrow.
12. Screening blood tests must be done before treatment begins. These are available from Regenecell.
13. Genuine stem cell treatment with any basis in medical science cannot be done for significantly less than $20 000. The production and testing costs alone are a significant portion of this. If you are being quoted less you might get less than you expected.
14. There are no supplements that will enhance treatment responses or make you own stem cells leave your bone marrow and magically repair your disease. However, taking good supplements is recommended by the American Medical Association and Regenecell endorses this.
15. No less than 30 million cells should be used in a complete treatment. No extra benefit has ever been shown with higher numbers.
16. Do not accept a company's claim that cells can be posted to you. Stem cells need to be cryopreserved to retain their efficacy, and specialised cryocouriers are used who ensure this cryo-chain is never broken. Also, importing biologicals across state borders, especially into the USA, is illegal and carries severe penalties for you and your doctor.
17. No stem cell company has FDA approval. They might use FDA approved processes in the production of their product, but that is as far as it goes.
18. Don't wait too long. The later in the disease process or the more damage you have, the more work there is for the cells to do, and the less benefit you will derive. This is especially true of diseases that progress rapidly. Please print this out and use it to guage the quality of the company you are communicating with and if you have any questions that cannot be answered #howstemcellswork" here feel free to contact the author.
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