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Plavix Plavix, also known as clopidogrel bisulfate , is a medicine available in the form of tablets. It helps prevent the possibility of a heart attack by preventing the blood cells in blood from sticking together and form a clot. This not only prevent heart attack but also help in keeping the strokes away. Plavix is also used as an antiplatelet medicine. If the person has been diagnosed positive for Peripheral Artery Disease or Acute Coronary Syndrome (ACS), the risk of a stroke or heart attack is higher. Plavix takes care for the clot formation in the blood and prevent building up of blood pressure and helps prevent heart attack or stroke consequently. It is also indicated for people with non-ST segment Myocardial Infarction and Refractory Ischemia. How Plavix works? Most of the cases heart attack occurs due to blood clot that either slows the blood flow down due to congestion or blocks it. This builds pressure in the arteries which in turn put the pressure on heart as tension builds up in the arteries. Blood contains anticoagulant that prevents the blood from clotting. The clot should form when blood comes in contact with air by suppressing the activity of coagulant. This happen in case of an injury like wound. However when the coagulant in the blood starts working when in the arteries, the blood start to thicken and this builds tension in the arteries. Plavix prevents the coagulant to make the platelets in the blood to stick together and form clot. How is Plavix taken? Plavix is to be taken as advised by your doctor. If you have Peripheral Acute Coronary Syndrome, unstable agina, heart attack or stroke your doctor may ask you to take Plavix with aspirin . For patients with myocardial infarction, Plavix is administered once a day with dosage of 75-325mg. For non ST elevation ACS, 300 mg may be given for the first dose followed by 75 mg daily. Plavix could be given as per the requirement for regular dosage as needed or according to the diagnosis done by the doctor. It is available in bottles of 30, 90, 100 and 500 in strengths of 75 and 300mg tablets. Side Effects of using Plavix Plavix is a very safe drug and has been popular among doctors for over 12 years now. However some of the side effects that have been noticed and found to be associated with Plavix and aspirin together are bleeding at gastrointestinal and at puncture sites, intracranial hemorrhage, epistaxis, hematuria and bruise. It may also lead to aplastic anemia, thrombic thrombocytic purpura and pancytopenia. Some of the less serious side effects are fever and hemorrhage of operative wounds. It may also lead to liver failure, hepatitis, serum sickness, myalgia, althralgia, arthritis, confusion, hallucination, respiratory, thoracic and nervous system disorders. It may also lead to skin disorders like rashes, urticariam eczema, angioedema, skin bleeding and lichen planus. Precautions to be taken - As Plavix is known to cause severe bleeding, if the patient is to undergo a surgery, the use of Plavix should be discontinued 5 days before the surgery.
- Do not discontinue the use of Plavix as premature discontinuation may increase cardiovascular events.
- Pregnant or nursing mothers should always let their doctor know of their pregnancy or lactation before they start with Plavix
- If you are undergoing generic medication for renal, mental, nervous, respiratory or skin disorders, make sure you let your doctor know as this may further deteriorate the symptoms.
- If excessive bleeding occurs consult your doctor immediately.
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