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Acid reflux is also known as heartburn which happens then the sphincter situated at the lower side of the esophagus does not close properly. This makes the contents of the stomach like bile, food and acids enter the lower part of the esophagus especially after the meals. Person with acid reflux feels a burning sensation at the back of the breastbone and when it stays for a longer time it leads to ulceration and esophageal inflammation. The bile acids, stomach acids and acid reflux combined together might result in cell proliferation and even could be carcinogenic. Oxidative stress can be developed due to inflammation and the same way free radicals too can be formed in more numbers that they damage of DNA.
Recent studies have concluded that prolonged acid reflux can lead to esophageal cancer as a certain enzyme found to be significantly more in cancer cells which gets exposed to stomach acids and produces hydrogen peroxide in more quantities. Researchers found that NOX5-S is the enzyme which gets affected due to acid exposure producing stress on the cells there by activating the genes and damaging the DNA. And they strongly believe the same reaction might occur in the cells of the body. But then, the stomach acid's role is still controversial.
Researches also found that NOX5-S is seen more in the condition called Barrett's esophagus (pre cancerous condition) and also in esophageal cancer cells. When the enzyme NOX5 was removed, the hydrogen peroxide production was lowered. Since the sequence is known, it might be possible to slower down or even avoid cancer progression by blocking various steps.
Important risk factors involved with this kind of cancer are GERD or gastroesophageal reflux disease and related conditions like barrett's esophagus, tobacco use, diet less in vegetables and fruits, alcohol consumption and so on. Many researchers believe that detection of cancerous tumors are limited that understanding them and developing new methods for detecting and preventing them early has not yet been possible.
The occurrence of esophageal cancer and acid reflux can be prevented to some extent if the person susceptible to it make use of more antacids, take a short walk after eating meals, by eating small portions of meals, eat fresh vegetable and fruits and eat their last meal of the day before at least six hours prior to sleep, practice distressing techniques like meditation, yoga and so on. It is better to avoid any fruits and vegetables that contain more acid such as tomatoes and citrus fruits like lemon, lime, orange and so on.
Natural Remedies:
There are certain natural remedies that offer a promising cure for esophageal cancer. Along with the natural remedies and a well-researched different diet pattern, a few simple adjustments to your lifestyle can make a huge difference to your efforts for prolonging the life for several years. You can increase your chances of surviving esophagus cancer now by trying these proven natural remedies discussed here
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